David R. Epstein has been a member of our board of directors since July, 2024. Mr. Epstein currently serves as Chief Executive Officer and Chairman of the Board of Directors of Ottimo Pharma Limited and is the former Chief Executive Officer and Director of Seagen, Inc. (formerly Nasdaq: SGEN), from November 2022 until Seagen’s acquisition by Pfizer Inc. in December 2023. Previously, Mr. Epstein was a consultant and executive partner at Flagship Pioneering from January 2017 until October 2022. Prior to that, Mr. Epstein was Chief Executive Officer for Novartis Pharmaceuticals, a division of Novartis AG (NYSE: NVS). Early in his career, he was an associate in the strategy practice of consulting firm Booz, Allen and Hamilton. He also serves on the board of directors of Tempus AI Inc. (Nasdaq: TEM). since January 2024, and Valo Health, LLC, since September 2019. He has served as a director of a number of biotechnology companies, including OPY Acquisition Corp. I (formerly Nsadaq: OHAA),from October 2021 to December 2023, Senti Biosciences, Inc. (Nasdaq: SNTI), from June 2022 to June 2023, Dynamics Special Purpose Corp, Senti’s predecessor, from March 2021 to June 2022, Evelo Biosciences, Inc. from March 2017 to February 2023, Axcella Heath Inc. (formerly Nasdaq: AXLA) (formerly Axcella Therapeutics) from May 2019 to October 2022, Rubius Therapeutics Inc. (formerly Nasdaq: RUBY) from January 2017 to October 2022 and Shape Therapeutics, from May 2024 to April 2025. Mr. Epstein also serves and has served as a director at the non-profit Three Opinions Foundation Inc. and at South Florida’s Pelican Harbor Seabird Station. Mr. Epstein holds a B.S. in Pharmacy from Rutgers University College of Pharmacy and an M.B.A. in Finance and Marketing from Columbia University Graduate School of Business. We believe that Mr. Epstein is qualified to serve on our board of directors because of his extensive experience serving in executive roles in the life sciences industry and leading the development and commercialization of numerous therapeutics.